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When to Get Medical Help Immediately Call emergency services now if you have: Swelling of lips, tongue, face, or throat Hives spreading across the body Wheezing, stridor, or chest tightness Fainting or near-fainting with a fast, weak pulse Severe palpitations or an irregular heartbeat Sudden profound muscle weakness or inability to stand (possible severe hypokalemia) Chest pain or breathlessness at rest Get seen within the week for: Redness spreading from the injection site, drainage, or fever A site that’s hot and tender beyond 48 hours Worsening numbness, burning, or unsteady walking New vision changes Calf pain, swelling, or warmth in one leg Persistent vomiting or severe diarrhea One rule I’d hold firmly: neurological symptoms that get worse during treatment always need investigation, never just more injections