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In studies of Indian patients, common mutations include C813A in 19%, 62 G3182A in 16%, 63 C813A in 12%, 63 T33053 in 6%, 64 C2975A in 6%, 64 2977insA in 6%, 64 whereas in the Caucasians population, the most common mutation is H1069Q which accounts for 37–63% 12,15 of cases and is the basis for screening