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This was fully investigated in 1849, by British physician Thomas Addison, from which it acquired the common name of Addison's anemia

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Why It Matters High levels of urinary DPD indicate accelerated bone breakdown , which can occur in: Osteoporosis and osteopenia Postmenopausal bone loss Hyperparathyroidism Certain cancers with bone metastases Chronic corticosteroid use Monitoring DPD levels provides early warning of skeletal imbalance, often before bone density scans reveal significant changes