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Too much histamine in the body—often called histamine intolerance or mast-cell–driven histamine excess, can affect many systems at once, which is why it's so often misunderstood or misdiagnosed. What is histamine Histamine

However, if diarrhea becomes severe or persists beyond a few days, check in with a healthcare provider to make sure you're not dealing with something more serious

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This imbalance, combined with an overrepresentation of proinflammatory Gram-negative bacteria, may sustain a state of chronic low-grade inflammation [6,45]