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Abbreviations 1H-NMR: proton nuclear magnetic resonance GC-MS: gas chromatography-mass spectrometry LC-MS: liquid chromatography-mass spectrometry LDL: low-density lipoprotein UHPLC-QTOF-MS: ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry Declarations Acknowledgments The authors are thankful to Professor Abdul Wadood, former director, National Institute of Unani Medicine, Bengaluru, for giving us the opportunity to explore this medicinal fruit plant, and Mr

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Quantity:30 ml

Cancer-linked CGI hypermethylation in already repressed promoters Introduction of high levels of DNA methylation throughout an active CpG-rich promoter region of protein-coding or non-coding genes (ncRNA genes) is almost always associated with repression of that gene’s transcription unless the gene contains an alternative unmethylated promoter (Figure 1a, f) [19,33,58,59]