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Briefly, after entering the mitochondria via a carrier for basic amino acids (SLC25A29), 2-aminoadipic acid semialdehyde (AASA) synthase, a bifunctional enzyme with domains for lysine–ketoglutarate reductase and saccharopine dehydrogenase, catalyzes the gradual conversion of lysine to saccharopine and AASA (allysine)

though results will vary based on individual commitment to exercise and diet.