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Similarly, the methylated derivative of resveratrol, pterostilbene, has been observed to upregulate Nrf2, HO-1, GSH, and GPX4 while reducing ACSL4 expression and iron content in H 2 O 2 -treated COV434 and KGN cells, suggesting a potential anti-ferroptotic effect ( In addition to the Nrf2/HO-1/GPX4 pathway, other pathways have been implicated

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This "one-two punch" is a great way to support long-term wellness, especially for those who train hard or live in high-stress environments

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