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By way of example, Immune-Mediated Inflammatory disease, which includes Inflammatory Bowel Disease (IBD) and other varieties of gut dysbiosis, may lead to increased intestinal permeability, which allows the initiation and progression of osteoporosis

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This highlights the potential of targeting Kla 'writers', 'erasers' or 'readers' to selectively induce ferroptosis in cancer cells, thereby enhancing the efficacy of cancer therapies while minimizing damage to normal tissues