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The agency’s modern-day role was defined in 1962, after thalidomide caused birth defects in thousands of babies around the world

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Furthermore, cytokines released by astrocytes may bind to their specific receptors in the dopaminergic neurons, such as TNFR1 and 2, and activate proapoptotic mechanisms through the activation of caspase 3, caspase 8, and cytochrome c [10]