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militaris FXR farnesoid X receptor GDS ginseng diol saponin GRP78 glucose-regulated protein78 GSO ginseng seed oil GWDF ginseng water-soluble dietary fiber HDL-C high density lipoprotein cholesterol HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase HOMA-IR insulin resistance index IL interleukin IR insulin resistance JNK c-Jun N-terminal kinase LDL low density lipid protein LDL-C low density lipoprotein cholesterol LDs lipid droplets LFG lactobacillus fermentum KP-3 fermented ginseng LXR liver X receptor MDA malondialdehyde MFG monascus ruber fermented ginseng NAFLD non-alcoholic fatty liver disease NASH non-alcoholic steatohepatitis NF-κB nuclear factor kappa-B NLRP3 nod-like receptor thermal protein domain associated protein 3 Nrf2 nuclear factor-erythroid 2 related factor 2 PGC-1α peroxisome proliferators-activated receptor γ co-activator α PI3K phosphatidylinositol-3-kinase PPAR peroxisome proliferator-activated receptor PPD protopanaxadiol PPT protopanaxatriol RG red ginseng ROS reactive oxygen species SCD-1 stearoyl-coenzyme A desaturase-1 SIRT sirtuins SOD superoxide dismutase SREBP sterol-regulatory element binding protein STAT signal transducer and activator of transcription TC total cholesterol TCM traditional Chinese medicine TG triglyceride TIMP tissue inhibitor of metalloproteinase 1 TNF-α tumor necrosis factor α UPR unfolded protein response WGCM wild ginseng cambial meristematic cells References Aron-Wisnewsky J., Vigliotti C., Witjes J., Le P., Holleboom A

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