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Furthermore, resonances arising from de novo-synthesized purine nucleotides (AXP) and components of the hexosamine pathway (e.g., UDP-GlcNAc, UDP-GalNAc, GlcNAc-1-P), which contribute to resistance of cancer stem cells to chemotherapy [24, 25], indicate enhanced distribution of glycolytic intermediates in the pentose phosphate pathway (via glucose-6-phosphate (G6P)) and hexosamine biosynthetic pathway (via fructose-6-phosphate (F6P))

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