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Research in PMC shows that IGF-1 makes satellite cells: Multiply (create more stem cells) Mature (turn into muscle cells) Fuse (merge with existing muscle or form new fibers) When satellite cells fuse together or merge with existing muscle fibers, you get actual new muscle tissue

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[DOI] [PMC free article] [PubMed] [Google Scholar] 198.Lin W., Wu R.T., Wu T., Khor T.O., Wang H., Kong A.N