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Improvement also occurred for hydration (83.3%), laxity (81.5%), and dryness (80.8%), suggesting clear evidence of enhanced moisture and skin firmness

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Phenotypic classification (LOAD vs nondementia [ND]) was determined on the basis of clinicopathological features, including neuritic plaque load (CERAD score), neurofibrillary tangle pathology (Braak stage), and cognitive status (Cogdx and DCFDX) (Fig